崎山真幸の業績一覧


  1. Y. Kawamura, H. Nakaoka, A. Nakayama, Y. Okada, K. Yamamoto, T. Higashino, M. Sakiyama, T. Shimizu, H. Ooyama, K. Ooyama, M. Nagase, Y. Hidaka, Y. Shirahama, K. Hosomichi, Y. Nishida, I. Shimoshikiryo, A. Hishida, S. Katsuura-Kamano, S. Shimizu, M. Kawaguchi, H. Uemura, R. Ibusuki, M. Hara, M. Naito, M. Takao, M. Nakajima, S. Iwasawa, H. Nakashima, K. Ohnaka, T. Nakamura, B. Stiburkova, T. R. Merriman, M. Nakatochi, S. Ichihara, M. Yokota, T. Takada, T. Saitoh, Y. Kamatani, A. Takahashi, K. Arisawa, T. Takezaki, K. Tanaka, K. Wakai, M. Kubo, T. Hosoya, K. Ichida, I. Inoue, N. Shinomiya, H. Matsuo. Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout. Ann. Rheum. Dis. (2019) (epub ahead of print)

  2. M. Sakiyama, H. Matsuo, A. Akashi, S. Shimizu, T. Higashino, M. Kawaguchi, A. Nakayama, M. Naito, S. Kawai, H. Nakashima, Y. Sakurai, K. Ichida, T. Shimizu, H. Ooyama, N. Shinomiya. Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout. Sci Rep. 7. 2500 (2017).

  3. H. Matsuo, T. Tsunoda, K. Ooyama, M. Sakiyama, T. Sogo, T. Takada, A. Nakashima, A. Nakayama, M. Kawaguchi, T. Higashino, K. Wakai , H. Ooyama, R. Hokari, H. Suzuki, K. Ichida, A.Inui, S. Fujimori, N. Shinomiya.　Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2.　Sci. Rep. 6, 31003 (2016).

  4. M. Sakiyama, H. Matsuo, H. Nakaoka, K. Yamamoto, A. Nakayama, T. Nakamura, S. Kawai, R. Okada, H. Ooyama, T. Shimizu, N. Shinomiya. Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus. Sci. Rep. 6, 25360 (2016).

  5. M. Sakiyama, H. Mastuo, S. Shimizu, H. Nakashima, T. Nakamura, A. Nakayama, T. Higashino, M. Naito, S. Suma, A. Hishida, T. Satoh, Y. Skurai, T. Takada, K. Ichida, H. Ooyama, T. Shimizu, N. Shinomiya, The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression. Sci. Rep. 6, 20148 (2016).

  6. Honkura Y, Matsuo H, Murakami S, Sakiyama M, Mizutari K, Shiotani A, Yamamoto M, Morita I, Shinomiya N, Kawase T, Katori Y, Motohashi H. NRF2 is a key target for prevention of noise-induced hearing loss by reducing oxidative damage of cochlea. Sci Rep. 6: 19329, 2016.

  7. Matsuo H#, Yamamoto K#, Nakaoka H#, Nakayama A#, Sakiyama M#, Chiba T, Takahashi A, Nakamura T, Nakashima H, Takada Y, Danjoh I, Shimizu S, Abe J, Kawamura Y, Terashige S, Ogata H, Tatsukawa S, Yin G, Okada R, Morita E, Naito M, Tokumasu A, Onoue H, Iwaya K, Ito T, Takada T, Inoue K, Kato Y, Nakamura Y, Sakurai Y, Suzuki H, Kanai Y, Hosoya T, Hamajima N, Inoue I, Kubo M, Ichida K, Ooyama H, Shimizu T, Shinomiya N. Genome-wide association study of clinically-defined gout identifies multiple risk loci and its association with clinical subtypes. Ann Rheum Dis 75, 652-659 (2016) (epub ahead of print on Feb 2nd, 2015) (#: co-first author)

  8. Sakiyama M, Kawakubo Y. Preventable frostbite due to cold pack. International Wound Journal 12(3): 366, 2015.

  9. Matsuo H, Tomiyama H, Satake W, Chiba T, Onoue H, Kawamura Y, Nakayama A, Shimizu S, Sakiyama M, Funayama M, Nishioka K, Shimizu T, Kaida K, Kamakura K, Toda T, Hattori N, Shinomiya N. ABCG2 variant has opposing effects on onset ages of Parkinson's disease and gout. Annals of Clinical and Translational Neurology 2(3): 302-6, 2015.

  10. Chiba T, Matsuo H, Sakiyama M, Nakayama A, Shimizu S, Wakai K, Suma S, Nakashima H, Sakurai Y, Shimizu T, Ichida K, Shinomiya N. Common variant of ALPK1 is not associated with gout: a replication study. Human Cell 28(1):1-4, 2015.

  11. Chiba T, Matsuo H, Kawamura Y, Nagamori S, Nishiyama T, Wei L, Nakayama A, Nakamura T, Sakiyama M, Takada T, Taketani Y, Suma S, Naito M, Oda T, Kumagai H, Moriyama Y, Ichida K, Shimizu T, Kanai Y, Shinomiya N. NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout. Arthritis & Rheumatology 67(1):281-287, 2015.

  12. 崎山真幸, 松尾洋孝. 若くして痛風を発症する遺伝子要因. Bio Clinica 30(5): 91-94, 2015.

  13. Sakiyama M, Matsuo H, Takada Y, Nakamura T, Nakayama A, Takada T, Kitajiri S, Wakai K, Suzuki H, Shinomiya N. Ethnic differences in ATP-binding cassette tansporter, sub-family G, member 2 (ABCG2/BCRP): Genotype combinations and estimated functions. Drug Metabolism and Pharmacokinetics 29(6): 490-492, 2014.

  14. Sakiyama M, Matsuo H, Chiba T, Nakayama A, Nakamura T, Shimizu S, Morita E, Fukuda N, Nakashima H, Sakurai Y, Ichida K, Shimizu T, Shinomiya N. Common variants of cGKII/PRKG2 are not associated with gout susceptibility. The Journal of Rheumatology 41(7): 1395-1397, 2014.

  15. Sakiyama M, Maeshima H, Higashino T, Kawakubo Y. Photolocalized varicella in an adult. British Journal of Dermatology 170(5): 1195-1196, 2014.

  16. Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakayama A, Chiba T, Naito M, Takada T, Suzuki H, Hamajima N, Ichida K, Shimizu T, Shinomiya N. A common variant of organic anion transporter 4 (OAT4/SLC22A11) gene is associated with renal underexcretion type gout. Drug Metabolism and Pharmacokinetics 29(2): 208-210, 2014.

  17. Sakiyama M, Matsuo H, Shimizu S, Chiba T, Nakayama A, Takada Y, Nakamura T, Takada T, Morita E, Naito M, Wakai K, Inoue H, Tatsukawa S, Sato J, Shimono K, Makino T, Satoh T, Suzuki H, Kanai Y, Hamajima N, Sakurai Y, Ichida K, Shimizu T, Shinomiya N. A common variant of leucine-rich repeat containing 16A (LRRC16A) gene is associated with gout susceptibility. Human Cell 27(1): 1-4, 2014.

  18. Sakiyama M, Maeda M, Fujimoto N, Satoh T. Eruptive syringoma localized on intertriginous area. Journal der Deutschen Dermatologischen Gesellschaft 12(1): 72-73, 2014.

  19. Takada Y, Matsuo H, Nakayama A, Sakiyama M, Hishida A, Okada R, Sakurai Y, Shimizu T, Ichida K, Shinomiya N. Common variant of PDZK1, adaptor protein gene of urate transporters, is not associated with gout. The Journal of Rheumatology 41(11): 2330-2331, 2014.

  20. Nakayama A, Matsuo H, Nakaoka H, Nakamura T, Nakashima H, Takada Y, Oikawa Y, Takada T, Sakiyama M, Shimizu S, Kawamura Y, Chiba T, Abe J, Wakai K, Kawai S, Okada R, Tamura T, Shichijo Y, Akashi A, Suzuki H, Hosoya T, Sakurai Y, Ichida K, Shinomiya N. Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors. Scientific Reports 4: 5227, 2014.

  21. Matsuo H, Takada T, Nakayama A, Shimizu T, Sakiyama M, Shimizu S, Chiba T, Nakashima H, Nakamura T, Takada Y, Sakurai Y, Hosoya T, Shinomiya N, Ichida K. ABCG2 dysfunction increases the risk of renal overload hyperuricemia. Nucleosides, Nucleotides and Nucleic Acids 33(4-6): 266-274, 2014.

  22. Chiba T, Matsuo H, Nagamori S, Nakayama A, Kawamura Y, Shimizu S, Sakiyama M, Hosoyamada M, Kawai S, Okada R, Hamajima N, Kanai Y, Shinomiya N. Identification of a hypouricemia patient with SLC2A9 R380W, a pathogenic mutation for renal hypouricemia type 2. Nucleosides, Nucleotides and Nucleic Acids 33(4-6): 261-265, 2014.

  23. Nakayama A, Matsuo H, Shimizu T, Takada Y, Nakamura T, Shimizu S, Chiba T, Sakiyama M, Naito M, Morita E, Ichida K, Shinomiya N. Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility. Rheumatology International 34(4): 473-476, 2014.

  24. Matsuo H, Nakayama A, Sakiyama M, Chiba T, Shimizu S, Kawamura Y, Nakashima H, Nakamura T, Takada Y, Oikawa Y, Takada T, Nakaoka H, Abe J, Inoue H, Wakai K, Kawai S, Guang Y, Nakagawa H, Ito T, Niwa K, Yamamoto K, Sakurai Y, Suzuki H, Hosoya T, Ichida K, Shimizu T, Shinomiya N. ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload. Scientific Reports 4: 3755, 2014.

  25. 崎山真幸, 高井彩也華, 今長慶志, 藤本典宏, 多島新吾. 角層下膿疱症に対するNarrow-band UVB療法. 皮膚科の臨床 56(13): 2116-2117, 2014.

  26. 崎山真幸, 藪田潤子, 阿部浩之, 藤本典宏, 佐藤貴浩, 多島新吾. 柵状被包性神経腫の一例. 皮膚科の臨床 56(2): 280-281, 2014.

  27. 崎山真幸, 藤本典宏, 阿部浩之, 多島新吾. 再発性多発性軟骨炎の1例. 皮膚科の臨床 56(1): 3-4, 2014.

  28. 永田由子, 崎山真幸, 薮田潤子, 青木繁, 藤本典宏, 小林孝志, 多島新吾. 骨髄転移をきたした有棘細胞癌. 皮膚科の臨床 56(9): 1352-1355, 2014.

  29. 高田 雄三, 松村 耕治, 松尾 洋孝, 中山 昌喜, 清水 聖子, 崎山真幸, 千葉 俊周, 四ノ宮 成祥, 中島 宏, 櫻井 裕, 清水 徹, 宮平 靖. 痛風・高尿酸血症のリスク評価のための迅速遺伝子検査 DNA多型 22(1): 151-154, 2014.

  30. 吉田幸代, 武藤文之介, 芝容平, 崎山真幸, 藤本典宏, 佐藤貴浩. 皮膚浸潤を認めたIgGκ型多発性骨髄腫の1例. 皮膚科の臨床 56(5): 761-764, 2014.

  31. 水口将志, 崎山真幸, 薮田 潤子, 藤本 典宏, 佐藤 貴浩, 多島 新吾. Nodular-cystic fat necrosisの3例. 臨床皮膚科 68(4): 303-306, 2014.

  32. 藪田潤子, 崎山真幸, 藤本典宏, 多島新吾. 外傷が誘因と考えられた爪下表皮嚢腫. 皮膚科の臨床 56(4): 682-683, 2014.

  33. 崎山とも, 平井郁子, 木花光, 黄聖琥, 崎山真幸. 悪性化した巨大尖圭コンジローマの1例. 臨床皮膚科 68(3): 255-258, 2014.

  34. 芝容平, 崎山真幸, 高橋英至, 藤本典宏, 佐藤貴浩. イミキモド5％クリーム外用が奏効したボーエン病の1例. 皮膚科の臨床 56(3): 450-453, 2014.

  35. Nakayama A, Matsuo H, Shimizu T, Ogata H, Takada Y, Nakashima H, Nakamura T, Shimizu S, Chiba T, Sakiyama M, Ushiyama C, Takada T, Inoue K, Kawai S, Hishida A, Wakai K, Hamajima N, Ichida K, Sakurai Y, Kato Y, Shimizu T, Shinomiya N. A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility. Human Cell 26(4): 133-136, 2013.

  36. Takada Y, Matsuo H, Sakiyama M, Nakayama A, Fuji A, Shimizu S, Chiba T, Nakasima H, Matsumura K, Suzuki K, Hamajima N, Niwa K, Suzuki S, Uchino S, Kobayashi Y, Shinomiya N. ABCG2 SNP typing using HRM assay: Effective approach for gout and hyperuricemia risk evaluation. Journal of Clinical Welfare 10: 64-69, 2013.

  37. Matsuo H, Ichida K, Takada T, Nakayama A, Nakashima H, Nakamura T, Kawamura Y, Takada Y, Yamamoto K, Inoue H, Oikawa Y, Naito M, Hishida A, Wakai K, Okada C, Shimizu S, Sakiyama M, Chiba T, Ogata H, Niwa K, Hosoyamada M, Mori A, Hamajima N, Suzuki H, Kanai Y, Sakurai Y, Hosoya T, Shimizu T, Shinomiya N. Common dysfunctional variants in ABCG2 are a major cause of early-onset gout. Scientific Reports 3: 2014, 2013.

  38. 崎山真幸, 高井彩也華, 藤本典宏, 佐藤貴浩, 多島新吾. エリスロマイシンとNarrow-band UVBが奏効した急性痘瘡状苔癬状粃糠疹. 皮膚科の臨床 55(9): 1079-1080, 2013.

  39. 崎山真幸, 前嶋啓孝, 川久保洋. Metastatic tuberculous abscess. Visual Dermatology 12(9): 932-933, 2013.

  40. 崎山真幸, 藤本典宏, 芝容平, 佐藤貴浩, 多島新吾. Cole-Engman症候群の1例. 皮膚科の臨床 55(8): 943-944, 2013.

  41. 崎山真幸, 青木繁, 川久保千賀, 阿部浩之, 藤本典宏, 小林孝志, 佐藤貴浩, 多島新吾. 植皮術後の陰茎の固定・安静維持のための保定装置の利用. 皮膚科の臨床 55(6): 789-793, 2013.

  42. Sakiyama M, Kobayashi T, Nagata Y, Fujimoto N, Satoh T, Tajima S. Bullous pyoderma gangrenosum: A case report and review of the published work. Journal of Dermatology 39(12): 1010–1015, 2012.

  43. 崎山真幸, 今長慶志, 藤本典宏, 小林孝志, 佐藤貴浩, 多島新吾. 黄色爪症候群の１例. 皮膚科の臨床 54(8): 1051-1052, 2012.

  44. 崎山真幸. 水虫(足白癬)の予防、対処法 : 油断すると、怖い病気(蜂窩織炎など)にもつながる. 月刊消防 34(6): 80-83, 2012.

  45. 高井彩也華, 青木繁, 崎山真幸, 阿部浩之, 藤本典宏, 小林孝志, 多島新吾. 軟部腫瘍が疑われたchronic expanding hematomaの1例. 臨床皮膚科 66(13): 1059-1063, 2012.

  46. 阿部浩之, 浅野千賀, 崎山真幸, 青木繁, 藤本典宏, 小林孝志, 多島新吾. 鼻腔腫瘍切除と鼻中隔軟骨採取における鼻翼外側縁切開法. 皮膚科の臨床 54(6): 911-914, 2012.

  47. 東野俊英, 崎山真幸, 浅野千賀, 阿部浩之, 青木繁, 藤本典宏, 小林孝志, 多島新吾. 頸部に生じたヒアリン血管型Castlemanリンパ腫. 臨床皮膚科 65(10): 783-786, 2011.

  48. 崎山真幸, 藤本栄大, 藤本典宏, 小林孝志, 多島新吾. 幼児に生じたAshy Dermatosis. 皮膚科の臨床 53(4): 660-661, 2011.

  49. 崎山真幸, 芝容平, 浅野千賀, 藤本典宏, 小林孝志, 多島新吾. 潰瘍を伴ったアナフィラクトイド紫斑. 皮膚科の臨床 53(2): 182-183, 2011.

  50. 崎山真幸, 古田淳一, 川内康弘, 多島新吾, 大塚藤男. ヒドロクロロチアジドによる光線過敏型薬疹. 皮膚科の臨床 51(5): 661-663, 2009.

  51. 阿部浩之, 高井彩也華, 崎山真幸, 森澤有希, 岩崎純也, 小野公司, 福本瞳, 武藤潤, 藤本栄大, 青木繁, 藤本典宏, 小林孝志, 多島新吾. 検体重量290gであった特発性陰囊石灰沈着症の1例. 皮膚科の臨床 51(3): 438-439, 2009.

  52. 崎山真幸, 小林孝志, 酒井瞳, 阿部浩之, 藤本典宏, 多島新吾. ダイエット中に発症した色素性痒疹の１例. 皮膚科の臨床 50(3): 359-362, 2008.

  53. 崎山真幸, 酒井瞳, 阿部浩之, 藤本栄大, 藤本典宏, 黒田啓, 多島新吾. 左耳垂部に発生した有茎性Merkel細胞癌の１例. 皮膚科の臨床 50(2): 207-209, 2008.

  54. 崎山真幸, 糟谷有希, 酒井瞳, 武藤潤, 藤本典宏, 黒田啓, 多島新吾, 長谷川ゆり, 芝崎智子, 松田秀雄, 今給黎敏彦, 入江広弥. 妊婦に生じたアナフィラクトイド紫斑. 皮膚病診療 29(8): 931-934, 2007.