松尾洋孝の業績一覧

・論文

  1. C. Domenighetti, PE. Sugier, AAK. Sreelatha, C. Schulte, S. Grover, O. Mohamed, B. Portugal, P. May, DR. Bobbili, M. Radivojkov-Blagojevic, P. Lichtner, AB. Singleton, DG. Hernandez, C. Edsall, GD. Mellick, A. Zimprich, W. Pirker, E. Rogaeva, AE. Lang, S. Koks, P. Taba, S. Lesage, A. Brice, JC. Corvol, MC. Chartier-Harlin, E. Mutez, K. Brockmann, AB. Deutschländer, GM. Hadjigeorgiou, E. Dardiotis, L. Stefanis, AM. Simits, EM. Valente, S. Petrucci, S. Duga, L. Straniero, A. Zecchinelli, G. Pezzoli, L. Brighina, C. Ferrarese, G. Annesi, A. Quattrone, M. Gagliardi, H. Matsuo, Y. Kawamura, N. Hattori, K. Nishioka, SJ. Chung, YJ. Kim, P. Kolber, BP. van de Warrenburg, BR. Bloem, J. Aasly, M. Toft, L. Pihlstrøm, LC Guedes LC, Ferreira JJ, Bardien S, Carr J, Tolosa E, M. Ezquerra, P. Pastor, M. Diez-Fairen, K. Wirdefeldt, NL. Pedersen, C. Ran, AC. Belin, A. Puschmann, C. Hellberg, CE. Clarke, KE. Morrison, M. Tan, D. Krainc, LF. Burbulla, MJ. Farrer, R. Krüger, T. Gasser, M. Sharma, A. Elbaz; Comprehensive Unbiaised Risk Factor Assessment for Genetics and Environment in Parkinson’s Disease (Courage-PD) consortium. Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease. J Parkinsons Dis. (2021).

  2. Y. Kawamura, A. Nakayama, S. Shimizu, Y. Toyoda, Y. Nishida, A. Hishida, S. Katsuura-Kamano, K. Shibuya, T. Tamura, M. Kawaguchi, S. Suzuki, S. Iwasawa, H. Nakashima, R. Ibusuki, H. Uemura, M. Hara, K. Takeuchi, T. Takada, M. Tsunoda, K. Arisawa, T. Takezaki, K. Tanaka, K. Ichida, K. Wakai, N. Shinomiya, H. Matsuo. A Proposal for Practical Diagnosis of Renal Hypouricemia: Evidenced from Genetic Studies of Nonfunctional Variants of URAT1/SLC22A12 among 30,685 Japanese Individuals. Biomedicines.; 9(8):1012, (2021).

  3. A. Nakayama, Y. Kawamura, Y. Toyoda, S. Shimizu, M. Kawaguchi, Y. Aoki, K. Takeuchi, R. Okada, Y. Kubo, T. Imakiire, S. Iwasawa, H. Nakashima, M. Tsunoda, K. Ito, H. Kumagai, T. Takada, K. Ichida, N. Shinomiya, H. Matsuo. Genetic-epidemiological analysis of hypouricemia from 4,993 Japanese on nonfunctional variants of URAT1/SLC22A12 gene. Rheumatology (Oxford). (2021).

  4. M. Sakiyama, H. Matsuo, Y. Toyoda, Y. Yonekura, T. Ishikawa, A. Nakayama, T. Higashino, Y. Kawamura, N. Fujimoto, N. Shinomiya, T. Satoh. Porphyrin accumulation in humans with common dysfunctional variants of ABCG2, a porphyrin transporter: potential association with acquired photosensitivity. Hum Cell. 34(4):1082-1086, (2021).

  5. Y. Toyoda, Y. Kawamura, A. Nakayama, H. Nakaoka, T. Higashino, S. Shimizu, H. Ooyama, K. Morimoto, N. Uchida, R. Shigesawa, K. Takeuchi, I. Inoue, K. Ichida, H. Suzuki, N. Shinomiya, T. Takada, H. Matsuo. Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12. Rheumatology (Oxford). (2021).

  6. M. Nakatochi, Y. Toyoda, M. Kanai, A. Nakayama, Y. Kawamura, A. Hishida, H. Mikami, K. Matsuo, T. Takezaki, Y. Momozawa, Project TBJ, Y. Kamatani, S. Ichihara, N. Shinomiya, M. Yokota, K. Wakai, Y. Okada, H. Matsuo; Japan Uric Acid Genomics Consortium (Japan Urate). An X chromosome-wide meta-analysis based on Japanese cohorts revealed that non-autosomal variations are associated with serum urate. Rheumatology (Oxford). (2021).

  7. M. Ogura, Y. Toyoda, M. Sakiyama, Y. Kawamura, A. Nakayama, Y. Yamanashi, T. Takada, S. Shimizu, T. Higashino, M. Nakajima, M. Naito, A. Hishida, S. Kawai, R. Okada, M. Sasaki, M. Ayaori, H. Suzuki, K. Takata, K. Ikewaki, M. Harada-Shiba, N. Shinomiya, H. Matsuo. Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach. Hum Cell. 34(6):1727-1733, (2021)

  8. M. Kawaguchi, A. Nakayama, Y. Aoyagi, T. Nakamura, S. Shimizu, Y. Kawamura, M. Takao, T. Tamura, A. Hishida, M. Nagayoshi, M. Nagase, K. Ooyama, H. Ooyama, N. Shinomiya, H. Matsuo. Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population. Hum Cell. (2021).

  9. Y. Toyoda, T. Takada, H. Miyata, H. Matsuo, H. Kassai, K Nakao, M. Nakatochi, Y. Kawamura, S. Shimizu, N. Shinomiya, K. Ichida, M. Hosoyamada, A. Aiba, H. Suzuki. Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice. Proc Natl Acad Sci U S A. 117(31):18175-18177 (2020).

  10. Y. Kawamura, Y. Toyoda, T. Ohnishi, R. Hisatomi, T. Higashino, A. Nakayama, S. Shimizu, M. Yanagi, I. Kamimaki, R. Fujimaru, H. Suzuki, N. Shinomiya, T. Takada, H. Matsuo. Identification of a dysfunctional splicing mutation in the SLC22A12/URAT1 gene causing renal hypouricaemia type 1: a report on two families. Rheumatology (Oxford), 59(12):3988-3990 (2020).

  11. A. Nakayama, M. Nakatochi, Y. Kawamura, K. Yamamoto, H. Nakaoka, S. Shimizu, T. Higashino, T. Koyama, A. Hishida, K. Kuriki, M. Watanabe, T. Shimizu, K. Ooyama, H. Ooyama, M. Nagase, Y. Hidaka, D. Matsui, T. Tamura, T. Nishiyama, C. Shimanoe, S. Katsuura-Kamano, N. Takashima, Y. Shirai, M. Kawaguchi, M. Takao, R. Sugiyama, Y. Takada, T. Nakamura, H. Nakashima, M. Tsunoda, I. Danjoh, A. Hozawa, K. Hosomichi, Y. Toyoda, Y. Kubota, T. Takada, H. Suzuki, Blanka Stiburkova, T. J. Major, T. R. Merriman, N. Kuriyama, H. Mikami, T. Takezaki, K. Matsuo, S. Suzuki, T. Hosoya, Y. Kamatani, M. Kubo, K. Ichida, K. Wakai, I. Inoue, Y. Okada, N. Shinomiya, H. Matsuo on behalf of Japan Gout Genomics Consortium (Japan Gout). Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Ann. Rheum. Dis.  79:657-665 (2020). (epub ahead of print on Apr. 1, 2020).

  12. A. Akashi, A. Nakayama, Y. Kamatani, T. Higashino, S. Shimizu, Y. Kawamura, M. Imoto, M. Naito, A. Hishida, M. Kawaguchi, M. Takao, M. Matsuo, T. Takada, K. Ichida, H. Ooyama, N. Shinomiya, H. Matsuo, A common variant of LDL receptor related protein 2 (LRP2) gene is associated with gout susceptibility: a meta-analysis in a Japanese population. Hum Cell 33, 303-307 (2020).

  13. T. Higashino, K. Morimoto, H. Nakaoka, Y. Toyoda, Y. Kawamura, S. Shimizu, T. Nakamura, K. Hosomichi, A. Nakayama, K. Ooyama, H. Ooyama, T. Shimizu, M. Ueno, T. Ito, T. Tamura, M. Naito, H. Nakashima, M. Kawaguchi, M. Takao, Y. Kawai, N. Osada, K. Ichida, K. Yamamoto, H. Suzuki, N. Shinomiya, I. Inoue, T. Takada, H. Matsuo, Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels. Ann. Rheum. Dis. 79, 164-166 (2020) (epub ahead of print on Nov 28, 2019.).

  14. A. Nakayama, H. Matsuo, A. Ohtahara, K. Ogino, M. Hakoda, T. Hamada, M. Hosoyamada, S. Yamaguchi, I. Hisatome, K. Ichida, N. Shinomiya, Clinical practice guideline for renal hypouricemia (1st edition). Hum Cell 32, 83-87 (2019).

  15. Y. Kawamura, H. Nakaoka, A. Nakayama, Y. Okada, K. Yamamoto, T. Higashino, M. Sakiyama, T. Shimizu, H. Ooyama, K. Ooyama, M. Nagase, Y. Hidaka, Y. Shirahama, K. Hosomichi, Y. Nishida, I. Shimoshikiryo, A. Hishida, S. Katsuura-Kamano, S. Shimizu, M. Kawaguchi, H. Uemura, R. Ibusuki, M. Hara, M. Naito, M. Takao, M. Nakajima, S. Iwasawa, H. Nakashima, K. Ohnaka, T. Nakamura, B. Stiburkova, T. R. Merriman, M. Nakatochi, S. Ichihara, M. Yokota, T. Takada, T. Saitoh, Y. Kamatani, A. Takahashi, K. Arisawa, T. Takezaki, K. Tanaka, K. Wakai, M. Kubo, T. Hosoya, K. Ichida, I. Inoue, N. Shinomiya, H. Matsuo. Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout. Ann. Rheum. Dis. 78, 1430-1437 (2019) (epub ahead of print on Jul. 8, 2019).

  16. M. Sakiyama, H. Matsuo, A. Akashi, S. Shimizu, T. Higashino, M. Kawaguchi, A. Nakayama, M. Naito, S. Kawai, H. Nakashima, Y. Sakurai, K. Ichida, T. Shimizu, H. Ooyama, N. Shinomiya. Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout. Sci Rep, 7, 2500 (2017).

  17. A. Nakayama, H. Nakaoka, K. Yamamoto, M. Sakiyama, A. Shaukat, Y. Toyoda, Y. Okada, Y. Kamatani, T. Nakamura, T. Takada, K. Inoue, T. Yasujima, H. Yuasa, Y. Shirahama, H. Nakashima, S. Shimizu, T. Higashino, Y. Kawamura, H. Ogata, M. Kawaguchi, Y. Ohkawa, I. Danjoh, A. Tokumasu, K. Ooyama, T. Ito, T. Kondo, K. Wakai, B. Stiburkova, K. Pavelka, L. K. Stamp, N. Dalbeth, Eurogout Consortium, Y. Sakurai, H. Suzuki, M. Hosoyamada, S. Fujimori, T. Yokoo, T. Hosoya, I. Inoue, A. Takahashi, M. Kubo, H. Ooyama, T. Shimizu, K. Ichida, N. Shinomiya, T. R. Merriman, H. Matsuo. GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes. Ann Rheum Dis, 76, 869-877 (2017). (epub ahead of print, on Nov 29, 2016).

  18. H. Matsuo, T. Tsunoda, K. Ooyama, M. Sakiyama, T. Sogo, T. Takada, A. Nakashima, A. Nakayama, M. Kawaguchi, T. Higashino, K. Wakai , H. Ooyama, R. Hokari, H. Suzuki, K. Ichida, A.Inui, S. Fujimori, N. Shinomiya.　Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2.　Sci Rep, 6, 31003 (2016).

  19. M. Sakiyama, H. Matsuo, H. Nakaoka, K. Yamamoto, A. Nakayama, T. Nakamura, S. Kawai, R. Okada, H. Ooyama, T. Shimizu, N. Shinomiya. Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus. Sci Rep, 6, 25360 (2016).

  20. M. Sakiyama, H. Mastuo, S. Shimizu, H. Nakashima, T. Nakamura, A. Nakayama, T. Higashino, M. Naito, S. Suma, A. Hishida, T. Satoh, Y. Skurai, T. Takada, K. Ichida, H. Ooyama, T. Shimizu, N. Shinomiya, The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression. Sci Rep, 6, 20148 (2016).

  21. Y. Honkura, H. Matsuo, S. Murakami, M. Sakiyama, K. Mizutari, A. Shiotani, M. Yamamoto, I. Morita, N. Shinomiya, T. Kawase, Y. Katori, H. Motohashi, NRF2 is a key target for prevention of noise-induced hearing loss by reducing oxidative damage of cochlea. Sci Rep, 6, 19329 (2016).

  22. H. Yokokawa, H. Fukuda, A. Suzuki, K. Fujibayashi, T. Naito, Y. Uehara, A. Nakayama, H. Matsuo, H. Sanada, P. A. Jose, Y. Miwa, T. Hisaoka, H. Isonuma, Association Between Serum Uric Acid Levels/Hyperuricemia and Hypertension Among 85,286 Japanese Workers. J Clin Hypertens (Greenwich), 18, 53-59 (2016).

  23. H. Matsuo, K. Yamamoto, H. Nakaoka, A. Nakayama, M. Sakiyama, T. Chiba, A. Takahashi, T. Nakamura, H. Nakashima, Y. Takada, I. Danjoh, S. Shimizu, J. Abe, Y. Kawamura, S. Terashige, H. Ogata, S. Tatsukawa, G. Yin, R. Okada, E. Morita, M. Naito, A. Tokumasu, H. Onoue, K. Iwaya, T. Ito, T. Takada, K. Inoue, Y. Kato, Y. Nakamura, Y. Sakurai, H. Suzuki, Y. Kanai, T. Hosoya, N. Hamajima, I. Inoue, M. Kubo, K. Ichida, H. Ooyama, T. Shimizu, N. Shinomiya, Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes. Ann Rheum Dis, 75, 652-659 (2016). (epub ahead of print, on Feb 2, 2015).

  24. H. Matsuo, H. Tomiyama, W. Satake, T. Chiba, H. Onoue, Y. Kawamura, A. Nakayama, S. Shimizu, M. Sakiyama, M. Funayama, K. Nishioka, T. Shimizu, K. Kaida, K. Kamakura, T. Toda, N. Hattori, N. Shinomiya, ABCG2 variant has opposing effects on onset ages of Parkinson's disease and gout. Ann Clin Transl Neurol, 2, 302-306 (2015).

  25. T. Chiba, H. Matsuo, Y. Kawamura, S. Nagamori, T. Nishiyama, L. Wei, A. Nakayama, T. Nakamura, M. Sakiyama, T. Takada, Y. Taketani, S. Suma, M. Naito, T. Oda, H. Kumagai, Y. Moriyama, K. Ichida, T. Shimizu, Y. Kanai, N. Shinomiya, NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout. Arthritis Rheumatol, 67, 281-287 (2015).

  26. T. Chiba, H. Matsuo, M. Sakiyama, A. Nakayama, S. Shimizu, K. Wakai, S. Suma, H. Nakashima, Y. Sakurai, T. Shimizu, K. Ichida, N. Shinomiya, Common variant of ALPK1 is not associated with gout: a replication study. Hum Cell, 28, 1-4 (2015).

  27. M. Taniguchi, H. Matsuo, S. Shimizu, A. Nakayama, K. Suzuki, N. Hamajima, N. Shinomiya, S. Nishio, S. Kosugi, S. Usami, J. Ito, S. Kitajiri, Carrier frequency of the GJB2 mutations that cause hereditary hearing loss in the Japanese population. J Hum Genet, 60, 613-617 (2015).

  28. J. Furukawa, K. Inoue, J. Maeda, T. Yasujima, K. Ohta, Y. Kanai, T. Takada, H. Matsuo, H. Yuasa, Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals. Sci Rep, 5, 15057 (2015).

  29. Y. Takada, H. Matsuo, A. Nakayama, M. Sakiyama, A. Hishida, R. Okada, Y. Sakurai, T. Shimizu, K. Ichida, N. Shinomiya, Common variant of PDZK1, adaptor protein gene of urate transporters, is not associated with gout. J. Rheumatol. 41, 2330-2331 (2014).

  30. T. Takada, K. Ichida, H. Matsuo, A. Nakayama, K. Murakami, Y. Yamanashi, H. Kasuga, N. Shinomiya, H. Suzuki, ABCG2 dysfunction increases serum uric acid by decreased intestinal urate excretion. Nucleosides Nucleotides Nucleic Acids, 33, 275-281 (2014).

  31. M. Sakiyama, H. Matsuo, Y. Takada, T. Nakamura, A. Nakayama, T. Takada, S. I. Kitajiri, K. Wakai, H. Suzuki, N. Shinomiya, Ethnic differences in ATP-binding cassette transporter, sub-family G, member 2 (ABCG2/BCRP): genotype combinations and estimated functions. Drug Metab Pharmacokinet, 29, 490-492 (2014).

  32. M. Sakiyama, H. Matsuo, S. Shimizu, H. Nakashima, A. Nakayama, T. Chiba, M. Naito, T. Takada, H. Suzuki, N. Hamajima, K. Ichida, T. Shimizu, N. Shinomiya, A common variant of organic anion transporter 4 (OAT4/SLC22A11) gene is associated with renal underexcretion type gout. Drug Metab Pharmacokinet, 29, 208-210 (2014).

  33. M. Sakiyama, H. Matsuo, S. Shimizu, T. Chiba, A. Nakayama, Y. Takada, T. Nakamura, T. Takada, E. Morita, M. Naito, K. Wakai, H. Inoue, S. Tatsukawa, J. Sato, K. Shimono, T. Makino, T. Satoh, H. Suzuki, Y. Kanai, N. Hamajima, Y. Sakurai, K. Ichida, T. Shimizu, N. Shinomiya, A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility. Hum Cell, 27, 1-4 (2014).

  34. M. Sakiyama, H. Matsuo, T. Chiba, A. Nakayama, T. Nakamura, S. Shimizu, E. Morita, N. Fukuda, H. Nakashima, Y. Sakurai, K. Ichida, T. Shimizu, N. Shinomiya, Common variants of cGKII/PRKG2 are not associated with gout susceptibility. J Rheumatol, 41, 1395-1397 (2014).

  35. A. Nakayama, H. Matsuo, T. Shimizu, Y. Takada, T. Nakamura, S. Shimizu, T. Chiba, M. Sakiyama, M. Naito, E. Morita, K. Ichida, N. Shinomiya, Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility. Rheumatol Int, 34, 473-476 (2014).

  36. A. Nakayama, H. Matsuo, H. Nakaoka, T. Nakamura, H. Nakashima, Y. Takada, Y. Oikawa, T. Takada, M. Sakiyama, S. Shimizu, Y. Kawamura, T. Chiba, J. Abe, K. Wakai, S. Kawai, R. Okada, T. Tamura, Y. Shichijo, A. Akashi, H. Suzuki, T. Hosoya, Y. Sakurai, K. Ichida, N. Shinomiya, Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors. Sci Rep, 4, 5227 (2014).

  37. H. Matsuo, T. Takada, A. Nakayama, T. Shimizu, M. Sakiyama, S. Shimizu, T. Chiba, H. Nakashima, T. Nakamura, Y. Takada, Y. Sakurai, T. Hosoya, N. Shinomiya, K. Ichida, ABCG2 dysfunction increases the risk of renal overload hyperuricemia. Nucleosides Nucleotides Nucleic Acids, 33, 266-274 (2014).

  38. H. Matsuo, A. Nakayama, M. Sakiyama, T. Chiba, S. Shimizu, Y. Kawamura, H. Nakashima, T. Nakamura, Y. Takada, Y. Oikawa, T. Takada, H. Nakaoka, J. Abe, H. Inoue, K. Wakai, S. Kawai, Y. Guang, H. Nakagawa, T. Ito, K. Niwa, K. Yamamoto, Y. Sakurai, H. Suzuki, T. Hosoya, K. Ichida, T. Shimizu, N. Shinomiya, ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload. Sci Rep, 4, 3755 (2014).

  39. T. Chiba, H. Matsuo, S. Nagamori, A. Nakayama, Y. Kawamura, S. Shimizu, M. Sakiyama, M. Hosoyamada, S. Kawai, R. Okada, N. Hamajima, Y. Kanai, N. Shinomiya, Identification of a hypouricemia patient with SLC2A9 R380W, a pathogenic mutation for renal hypouricemia type 2. Nucleosides Nucleotides Nucleic Acids, 33, 261-265 (2014).

  40. 高田雄三, 松村耕治, 松尾洋孝, 中山昌喜, 清水聖子, 崎山真幸, 千葉俊周, 四ノ宮成祥, 中島宏, 櫻井裕, 清水徹, 宮平靖, 痛風・高尿酸血症のリスク評価のための迅速遺伝子検査. DNA多型 22, 151-154 (2014).

  41. S. Takeuchi, K. Wada, T. Toyooka, N. Shinomiya, H. Shimazaki, K. Nakanishi, K. Nagatani, N. Otani, H. Osada, Y. Uozumi, H. Matsuo, H. Nawashiro, Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas. Neurosurgery, 72, 33-41; discussion. 41 (2013).

  42. Y. Takada, H. Matsuo, M. Sakiyama, A. Nakayama, A. Fujii, S. Shimizu, T. Chiba, H. Ogata, H. Nakashima, K. Matsumura, K. Suzuki, N. Hamajima, K. Niwa, S. Suzuki, S. Uchino, Y. Sakurai, Y. Kobayashi, N. Shinomiya, ABCG2 SNP typing using HRM assay : Effective approach for gout and hyperuricemia risk evaluation. J Clin Welfare, 10, 64-69 (2013).

  43. A. Nakayama, H. Matsuo, T. Shimizu, H. Ogata, Y. Takada, H. Nakashima, T. Nakamura, S. Shimizu, T. Chiba, M. Sakiyama, C. Ushiyama, T. Takada, K. Inoue, S. Kawai, A. Hishida, K. Wakai, N. Hamajima, K. Ichida, Y. Sakurai, Y. Kato, N. Shinomiya, A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility. Hum Cell, 26, 133-136 (2013).

  44. H. Matsuo, K. Ichida, T. Takada, A. Nakayama, H. Nakashima, T. Nakamura, Y. Kawamura, Y. Takada, K. Yamamoto, H. Inoue, Y. Oikawa, M. Naito, A. Hishida, K. Wakai, C. Okada, S. Shimizu, M. Sakiyama, T. Chiba, H. Ogata, K. Niwa, M. Hosoyamada, A. Mori, N. Hamajima, H. Suzuki, Y. Kanai, Y. Sakurai, T. Hosoya, T. Shimizu, N. Shinomiya, Common dysfunctional variants in ABCG2 are a major cause of early-onset gout. Sci Rep, 3, 2014 (2013).

  45. Y. Hinohara, M. Naito, R. Okada, G. Yin, T. Higashibata, T. Tamura, S. Kawai, E. Morita, K. Wakai, H. Matsuo, A. Mori, N. Hamajima, No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW. Nagoya J Med Sci, 75, 93-100 (2013).

  46. 中山昌喜, 松尾洋孝, 高田龍平, 市田公美, 四ノ宮成祥, 【日本が貢献した世界的新知見】 ABCG2と高尿酸血症. 高尿酸血症と痛風 21, 43-48 (2013).

  47. 高田雄三, 松村耕治, 小林靖, 松尾洋孝, 中山昌喜, 四ノ宮成祥, 中島宏, 櫻井裕, 鈴木康司, 濱嶋信之, 全自動SNPタイピング装置を利用した痛風の遺伝子タイピング. DNA多型, 21, 256-260 (2013).

  48. 森谷邦彦, 鈴木淳美, 鈴木大, 浅田洋司, 根本照子, 鈴木保志朗, 藤江弘美, 鈴木潤, 阿部淳子, 清水聖子, 松尾洋孝, 四ノ宮成祥, 腰痛を主訴に来院し、遺伝子解析により腎性低尿酸血症1型と診断された1例. 小児科臨床, 66, 1930-1932 (2013).

  49. S. Takeuchi, H. Nawashiro, K. Wada, N. Nomura, T. Toyooka, N. Otani, H. Osada, H. Matsuo, N. Shinomiya, L-Leucine induces growth arrest and persistent ERK activation in glioma cells. Amino Acids, 43, 717-724 (2012).

  50. K. Ichida, H. Matsuo, T. Takada, A. Nakayama, K. Murakami, T. Shimizu, Y. Yamanashi, H. Kasuga, H. Nakashima, T. Nakamura, Y. Takada, Y. Kawamura, H. Inoue, C. Okada, Y. Utsumi, Y. Ikebuchi, K. Ito, M. Nakamura, Y. Shinohara, M. Hosoyamada, Y. Sakurai, N. Shinomiya, T. Hosoya, H. Suzuki, Decreased extra-renal urate excretion is a common cause of hyperuricemia. Nat Commun, 3, 764 (2012).

  51. N. Hamajima, M. Naito, R. Okada, S. Kawai, G. Yin, E. Morita, T. Higashibata, T. Tamura, H. Nakagawa, H. Matsuo, A. Mori, K. Wakai, Significant interaction between LRP2 rs2544390 in intron 1 and alcohol drinking for serum uric acid levels among a Japanese population. Gene, 503, 131-136 (2012).

  52. 高田雄三, 松村耕治, 松尾洋孝, 井上寛規, 中山昌喜, 四ノ宮成祥, 藤井安宇美, 丹羽和紀, 鈴木康司, 濱嶋信之, 小林靖, High Resolution Melting法によるABCG2遺伝子のSNPタイピング. DNA多型, 20, 286-290 (2012).

  53. A. Nakayama, H. Matsuo, T. Takada, K. Ichida, T. Nakamura, Y. Ikebuchi, K. Ito, T. Hosoya, Y. Kanai, H. Suzuki, N. Shinomiya, ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans. Nucleosides Nucleotides Nucleic Acids, 30, 1091-1097 (2011).

  54. H. Matsuo, T. Takada, K. Ichida, T. Nakamura, A. Nakayama, Y. Takada, C. Okada, Y. Sakurai, T. Hosoya, Y. Kanai, H. Suzuki, N. Shinomiya, Identification of ABCG2 dysfunction as a major factor contributing to gout. Nucleosides Nucleotides Nucleic Acids, 30, 1098-1104 (2011).

  55. H. Matsuo, T. Takada, K. Ichida, T. Nakamura, A. Nakayama, H. Suzuki, T. Hosoya, N. Shinomiya, ABCG2/BCRP dysfunction as a major cause of gout. Nucleosides Nucleotides Nucleic Acids, 30, 1117-1128 (2011).

  56. Y. Kawamura, H. Matsuo, T. Chiba, S. Nagamori, A. Nakayama, H. Inoue, Y. Utsumi, T. Oda, J. Nishiyama, Y. Kanai, N. Shinomiya, Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2). Nucleosides Nucleotides Nucleic Acids, 30, 1105-1111 (2011).

  57. N. Hamajima, R. Okada, S. Kawai, A. Hishida, E. Morita, G. Yin, K. Wakai, H. Matsuo, H. Inoue, Y. Takada, Y. Asai, A. Mori, M. Naito, Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population. Mol Genet Metab, 103, 378-382 (2011).

  58. S. Watanabe, H. Matsuo, Y. Kobayashi, Y. Satoh, M. Fujita, A. Nakayama, Y. Aizawa, N. Shinomiya, S. Suzuki, Transient degradation of myelin basic protein in the rat hippocampus following acute carbon monoxide poisoning. Neurosci Res, 68, 232-240 (2010).

  59. K. Takeuchi, S. Ogata, K. Nakanishi, Y. Ozeki, S. Hiroi, S. Tominaga, S. Aida, H. Matsuo, T. Sakata, T. Kawai, LAT1 expression in non-small-cell lung carcinomas: analyses by semiquantitative reverse transcription-PCR (237 cases) and immunohistochemistry (295 cases). Lung Cancer, 68, 58-65 (2010).

  60. H. Matsuo, T. Takada, K. Ichida, T. Nakamura, A. Nakayama, Y. Ikebuchi, K. Ito, Y. Kusanagi, T. Chiba, S. Tadokoro, Y. Takada, Y. Oikawa, H. Inoue, K. Suzuki, R. Okada, J. Nishiyama, H. Domoto, S. Watanabe, M. Fujita, Y. Morimoto, M. Naito, K. Nishio, A. Hishida, K. Wakai, Y. Asai, K. Niwa, K. Kamakura, S. Nonoyama, Y. Sakurai, T. Hosoya, Y. Kanai, H. Suzuki, N. Hamajima, N. Shinomiya, Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population. Sci Transl Med, 1, 5-11 (2009).

  61. H. Matsuo, T. Chiba, S. Nagamori, A. Nakayama, H. Domoto, K. Phetdee, P. Wiriyasermkul, Y. Kikuchi, T. Oda, J. Nishiyama, T. Nakamura, Y. Morimoto, K. Kamakura, Y. Sakurai, S. Nonoyama, Y. Kanai, N. Shinomiya, Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia. Am J Hum Genet, 83, 744-751 (2008).

  62. K. Nakanishi, S. Ogata, H. Matsuo, Y. Kanai, H. Endou, S. Hiroi, S. Tominaga, S. Aida, H. Kasamatsu, T. Kawai, Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract. Virchows. Arch, 451, 681-690 (2007).

  63. N. Kondoh, N. Imazeki, M. Arai, A. Hada, K. Hatsuse, H. Matsuo, O. Matsubara, S. Ohkura, M. Yamamoto, Activation of a system A amino acid transporter, ATA1/SLC38A1, in human hepatocellular carcinoma and preneoplastic liver tissues. Int J Oncol, 31, 81-87 (2007).

  64. Y. Shigeta, Y. Kanai, A. Chairoungdua, N. Ahmed, S. Sakamoto, H. Matsuo, D. K. Kim, M. Fujimura, N. Anzai, K. Mizoguchi, T. Ueda, K. Akakura, T. Ichikawa, H. Ito, H. Endou, A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter. Kidney Int, 69, 1198-1206 (2006).

  65. H. Nawashiro, N. Otani, N. Shinomiya, S. Fukui, H. Ooigawa, K. Shima, H. Matsuo, Y. Kanai, H. Endou, L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors. Int J Cancer, 119, 484-492 (2006).

  66. N. Wakida, D. G. Tuyen, M. Adachi, T. Miyoshi, H. Nonoguchi, T. Oka, O. Ueda, M. Tazawa, S. Kurihara, Y. Yoneta, H. Shimada, T. Oda, Y. Kikuchi, H. Matsuo, M. Hosoyamada, H. Endou, M. Otagiri, K. Tomita, K. Kitamura, Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia. J Clin Endocrinol Metab, 90, 2169-2174 (2005).

  67. 松尾洋孝, 福田潤, ベールをぬいだ細胞膜輸送の分子機構―トランスポーター分子を標的とする疾患研究―. 防衛医科大学校雑誌, 30, 103-123 (2005).

  68. H. Matsuo, Y. Kanai, M. Tokunaga, T. Nakata, A. Chairoungdua, H. Ishimine, S. Tsukada, H. Ooigawa, H. Nawashiro, Y. Kobayashi, J. Fukuda, H. Endou, High affinity D- and L-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices. Neurosci Lett, 358, 123-126 (2004).

  69. Y. Morimoto, S. Kohyama, K. Nakai, H. Matsuo, F. Karasawa, M. Kikuchi, Long-term effects of UV light on contractility of rat arteries in vivo. Photochem Photobiol, 78, 372-376 (2003).

  70. H. Nawashiro, N. Otani, N. Shinomiya, S. Fukui, N. Nomura, A. Yano, K. Shima, H. Matsuo, Y. Kanai, The role of CD98 in astrocytic neoplasms. Hum Cell, 15, 25-31 (2002).

  71. H. Mochizuki, K. Kamakura, M. Kanzaki, T. Nishii, H. Matsuo, K. Motoyoshi, Somatosensory evoked potential in neurosyphilis. J Neurol, 249, 1220-1222 (2002).

  72. H. Matsuo, Y. Kanai, J. Y. Kim, A. Chairoungdua, D. K. Kim, J. Inatomi, Y. Shigeta, H. Ishimine, S. Chaekuntode, K. Tachampa, H. W. Choi, E. Babu, J. Fukuda, H. Endou, Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family associated with unknown heavy chains. J Biol Chem, 277, 21017-21026 (2002).

  73. D. K. Kim, Y. Kanai, H. Matsuo, J. Y. Kim, A. Chairoungdua, Y. Kobayashi, A. Enomoto, S. H. Cha, T. Goya, H. Endou, The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. Genomics, 79, 95-103 (2002).

  74. A. Enomoto, H. Kimura, A. Chairoungdua, Y. Shigeta, P. Jutabha, S. H. Cha, M. Hosoyamada, M. Takeda, T. Sekine, T. Igarashi, H. Matsuo, Y. Kikuchi, T. Oda, K. Ichida, T. Hosoya, K. Shimokata, T. Niwa, Y. Kanai, H. Endou, Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature, 417, 447-452 (2002).

  75. O. Yanagida, Y. Kanai, A. Chairoungdua, D. K. Kim, H. Segawa, T. Nii, S. H. Cha, H. Matsuo, J. Fukushima, Y. Fukasawa, Y. Tani, Y. Taketani, H. Uchino, J. Y. Kim, J. Inatomi, I. Okayasu, K. Miyamoto, E. Takeda, T. Goya, H. Endou, Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. Biochim Biophys Acta, 1514, 291-302 (2001).

  76. K. Mizoguchi, S. H. Cha, A. Chairoungdua, D. K. Kim, Y. Shigeta, H. Matsuo, J. Fukushima, Y. Awa, K. Akakura, T. Goya, H. Ito, H. Endou, Y. Kanai, Human cystinuria-related transporter: localization and functional characterization. Kidney Int, 59, 1821-1833 (2001).

  77. D. K. Kim, Y. Kanai, A. Chairoungdua, H. Matsuo, S. H. Cha, H. Endou, Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem, 276, 17221-17228 (2001).

  78. A. Chairoungdua, Y. Kanai, H. Matsuo, J. Inatomi, D. K. Kim, H. Endou, Identification and characterization of a novel member of the heterodimeric amino acid transporter family presumed to be associated with an unknown heavy chain. J Biol Chem, 276, 49390-49399 (2001).

  79. J. Nakauchi, H. Matsuo, D. K. Kim, A. Goto, A. Chairoungdua, S. H. Cha, J. Inatomi, Y. Shiokawa, K. Yamaguchi, I. Saito, H. Endou, Y. Kanai, Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports D-serine with high affinity. Neurosci Lett, 287, 231-235 (2000).

  80. H. Matsuo, S. Tsukada, T. Nakata, A. Chairoungdua, D. K. Kim, S. H. Cha, J. Inatomi, H. Yorifuji, J. Fukuda, H. Endou, Y. Kanai, Expression of a system L neutral amino acid transporter at the blood-brain barrier. Neuroreport, 11, 3507-3511 (2000).

  81. H. Matsuo, N. Shinomiya, S. Suzuki, Hyperbaric stress during saturation diving induces lymphocyte subset changes and heat shock protein expression. Undersea Hyperb Med, 27, 37-41 (2000).

  82. H. Matsuo, Y. Morimoto, T. Arai, M. Wada, R. Higo, S. Tabata, K. Nakai, M. Kikuchi, Heat and photolytic nitric oxide are essential factors for light-induced vascular tension changes. Lasers Med Sci, 15, 181-187 (2000).

  83. H. Matsuo, A. Chairoungdua, D. K. Kim, S. H. Cha, J. Fukuda, H. Endou, Y. Kanai, Mouse Asc-1 (asc-type amino acid transporter 1) maps to chromosome 7, region B1-B5. Chromosome Res, 8, 456 (2000).

  84. Y. Kanai, Y. Fukasawa, S. H. Cha, H. Segawa, A. Chairoungdua, D. K. Kim, H. Matsuo, J. Y. Kim, K. Miyamoto, E. Takeda, H. Endou, Transport properties of a system y+L neutral and basic amino acid transporter. Insights into the mechanisms of substrate recognition. J Biol Chem, 275, 20787-20793 (2000).

  85. Y. Fukasawa, H. Segawa, J. Y. Kim, A. Chairoungdua, D. K. Kim, H. Matsuo, S. H. Cha, H. Endou, Y. Kanai, Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids. J Biol Chem, 275, 9690-9698 (2000).

  86. H. Matsuo, K. Kamakura, M. Saito, M. Okano, T. Nagase, Y. Tadano, K. Kaida, A. Hirata, N. Miyamoto, T. Masaki, R. Nakamura, K. Motoyoshi, H. Tanaka, S. Tsuji, Familial paroxysmal dystonic choreoathetosis: clinical findings in a large Japanese family and genetic linkage to 2q. Arch Neurol, 56, 721-726 (1999).

  87. H. Matsuo, K. Kamakura, S. Matsushita, T. Ohmori, M. Okano, Y. Tadano, S. Tsuji, S. Higuchi, Mutational analysis of the anion exchanger 3 gene in familial paroxysmal dystonic choreoathetosis linked to chromosome 2q. Am J Med Genet, 88, 733-737 (1999).

  88. Y. Morimoto, T. Arai, H. Matsuo, M. Kikuchi, Possible mechanisms of vascular relaxation induced by pulsed-UV laser. Photochem Photobiol, 68, 388-393 (1998).

・著書

  1. 中山昌喜, 松尾洋孝, 四ノ宮成祥, 尿酸異常症の遺伝子発見から腎性低尿酸血症診療ガイドライン策定まで. 尿酸と血糖, 2(1), 43-46 (2016).

  2. 中山昌喜, 松尾洋孝, ABCG2遺伝子変異という遺伝要因は環境要因よりも影響力が大きい. 高尿酸血症と痛風, 23, 94 (2015).

  3. 中山昌喜, 松尾洋孝, 市田公美, 腎性低尿酸血症とその原因、対策. 最新医学 別冊 高尿酸血症・痛風　診断と治療のABCシリーズ, 105, 99-106 (2015).

  4. 松尾洋孝, 高田龍平, トランスポーター及びその薬物との関連について述べよ. カラーイラストで学ぶ　集中講義　薬理学, 16-17 (2015).

  5. 千葉俊周, 松尾洋孝, 市田公美, 四ノ宮成祥, 尿酸代謝におけるUp-to-Date(第8回)　痛風の遺伝子、基礎から臨床へ. 医薬の門, 53, 74-79 (2013).

  6. 高田龍平, 松尾洋孝, 市田公美, 尿酸排出トランスポーターと高尿酸血症の新たな発症メカニズム. 日本医事新報, 48-49 (2013).

  7. 高田龍平, 松尾洋孝, 【トランスポーターと疾患研究の最前線】 トランスポーターと疾患【尿酸】 ABCトランスポーターによる尿酸輸送. 医学のあゆみ, 245, 11-15 (2013).

  8. 中山昌喜, 松尾洋孝, 市田公美, 四ノ宮成祥, 【腎疾患治療マニュアル2012-13】 尿細管疾患　尿細管機能異常症　腎性低尿酸血症. 腎と透析, 72, 370-373 (2012).

  9. 千葉俊周, 松尾洋孝, 中山昌喜, 市田公美, 四ノ宮成祥, XV 膜輸送系の異常 遺伝性腎性低尿酸血症. 別冊 日本臨床 (日本臨床社, 大阪, ed. 2, 2012), vol. 新領域別症候群シリーズ 20, 807-811(2012).

  10. 千葉俊周, 松尾洋孝, 市田公美, 四ノ宮成祥, 【高尿酸血症・低尿酸血症Q&A】 低尿酸血症の頻度、原因、分類を教えてください. 腎と透析, 73, 301-304 (2012).

  11. 松尾洋孝, 市田公美, 高田龍平, 中山昌喜, 四ノ宮成祥, 尿酸動態の支配要因としての尿酸トランスポーター. 細胞工学, 31, 553-557 (2012).

  12. 松尾洋孝, 四ノ宮成祥, 代謝　臨床分野での進歩 腎性低尿酸血症の遺伝学. Annual Review糖尿病・代謝・内分泌 2012, 145-154 (2012).

  13. 松尾洋孝, 【臨床医のための高尿酸血症・痛風のABC】 その他　痛風の遺伝素因を教えてください. 高尿酸血症と痛風, 20, 84-86 (2012).

  14. 松尾洋孝, 【トランスポートソーム　生体膜輸送機構の全体像に迫る　基礎、臨床、創薬応用研究の最新成果】 残されたトランスポーターへのアプローチ　トランスポーターの分子機能を指標とした臨床遺伝学的解析による痛風の主要病因遺伝子ABCG2の同定. 遺伝子医学MOOK, 116-125 (2011).

  15. 松尾洋孝, 【尿酸】 高尿酸血症と腎輸送体. 腎臓 34, 16-22 (2011).

  16. 松尾洋孝, 第7章 尿酸のトランスポーター in 栄養・食品機能とトランスポーター, 日本栄養・食糧学会 監修, 竹谷豊, 薩秀夫, 伊藤美紀子, 武田英二, Eds. (建帛社, 東京, 2011), . 145-166 (2011).

  17. 松尾洋孝, 3-2-4 尿酸輸送 in トランスポートソームの世界 -膜輸送研究の源流から未来へ-, 金井好克, 竹島浩, 森泰生, 久保義弘, Eds. (特定領域研究「生体膜トランスポートソームの分子構築と生理機能」事務局, 大阪, 179-191 (2011).

  18. 高田龍平, 松尾洋孝, 尿酸排出トランスポーターABCG2/BCRPと痛風発症リスク. 生化学, 83, 1131-1135 (2011).

  19. 高田雄三, 松尾洋孝, 痛風・高尿酸血症の原因遺伝子(ABCG2). Medical Technology, 39, 884-886 (2011).

  20. 中山昌喜, 松尾洋孝, 四ノ宮成祥, 痛風の遺伝子. リウマチ科, 44, 689-694 (2010).

  21. 中山昌喜, 松尾洋孝, 四ノ宮成祥, 【痛風診療最前線】 発症原因　遺伝要因. Modern Physician, 30, 1385-1388 (2010).

  22. 松尾洋孝, 市田公美, 症例検討　症例を読む(第29回)　GLUT9の異常症. 高尿酸血症と痛風, 18, 84-89 (2010).

  23. 松尾洋孝, 高田龍平, 市田公美, 中村好宏, 鈴木洋史, 四ノ宮成祥, 痛風の主要な病因遺伝子ABCG2の同定. 実験医学. (羊土社, 東京), 28, 1285-1289 (2010).

  24. 松尾洋孝,尿酸の再吸収機構と輸送体病　ゲノムワイド関連解析後の新展開. Annual Review腎臓 2010, 9-20 (2010).

  25. 松尾洋孝, 痛風の病因遺伝子 in 痛風と核酸代謝, 34, 159-169 (2010)..

  26. T. Toyooka, H. Nawashiro, N. Shinomiya, A. Yano, H. Ooigawa, A. Ohsumi, Y. Uozumi, Y. Yanagawa, H. Matsuo, K. Shima, in Intracranial Pressure and Brain Monitoring., G. Manley, G. Hemphill, S. Stiver, Eds. (Springer Wien, New York), vol. XIII, 385-399 (2010).

  27. 松尾洋孝, 遺伝性発作性不随意運動の病因遺伝子の探索～チャネル・トランスポーター病としての見地から～. ブレインサイエンスレビュー 2004, 伊藤正雄, 川合述史, Eds. (クバプロ出版, 東京), 171-194 (2010).